Mantle Edge Syndrome

By | June 8, 2022

The coat edge syndrome is damage to the coat edge. This is accompanied by brain damage. This primarily causes a movement and sensitivity disorder in the legs.

What is mantle edge syndrome?

Mantle edge syndrome is a very rare condition. The longitudinal cleft of the cerebrum is called the mantle edge. The longitudinal fissure of the cerebri is the fissure that divides the cerebrum into two halves. The cerebrum is called the telencephalon and the two hemispheres are the right and left hemispheres. The edge of the mantle runs centrally above the brain from front to back. For amgs – abnormal mammary gland secretion, please visit

It forms the transition from the outer to the inner surface of the brain. The dura mater encephali is located in the edge of the mantle. Their job is to give the brain mechanical support. In the mantle edge syndrome there is damage to the mantle edge of the cerebral hemisphere. This means that the function of the superior cerebral margo, the blunt edge at the transition from the convex part of the cortex to the medial surface at the hemisphere, is impaired.

The consequences are primarily movement and sensitivity disorders in both legs. This can lead to parapatesis and consequent paralysis of the extremities. In addition, there is a micturition disorder in the patient. These are bladder emptying problems.


The most common cause of mantle edge syndrome is parasagittal meningioma. This is associated with spastic parapatesis of the legs and uncontrollable bladder emptying. A meningioma is a brain tumor that patients often develop in adulthood. It is diagnosed in most cases between the ages of 40 and 60.

Women are affected significantly more often than men. A meningioma is characterized by slow growth of the brain tumor and its suppressing appearance. For this reason, the cause of complaints is often only found after several months or years. In mantle edge syndrome, both hemispheres of the brain are affected. This leads to a dysfunction of cortical representation fields.

Compression of the meningioma on the cortex results in a contralateral or bilateral leg paresis. The contusion of the brain and thus the tissue damage can also have other causes. In extremely rare cases, the lesion of both hemispheres can be caused by external influences. This includes, for example, grazing shots in the middle of the crown.

Objects falling on the head can also cause damage to the edge of the jacket. The use of force, such as a severe blow to the crown of the head, can also cause cortical and mantle lesions.

Symptoms, Ailments & Signs

The symptoms of the coat edge syndrome mainly include sensorimotor paralysis of the legs and a bladder disorder. Uncontrolled emptying of the bladder occurs in the patient. In addition, the initial drop foot is documented. The foot-lifting muscles in the swing phase are disturbed.

This allows the leg to swing freely. As with leg paratese, one or both feet can be affected. Jackson’s seizures occur in some patients. These are focal epileptic seizures. Individual body regions or the extremities are affected. In extreme cases, an entire half of the body can be affected.

In the case of the lateral edge syndrome, disorders of the rectum can also occur. Analogous to the bladder disorder, only voluntary control over the external sphincter is lost. Gross neurological deficits also occur in mantle edge syndrome. These can all be traced back to functional disorders in the affected brain regions.

Diagnosis & disease progression

Diagnosing mantle edge syndrome is considered very difficult. It is often overlooked in investigations or not recognized over a long period of time and not properly assessed. The disease usually progresses over several years. The slow growth of the brain tumor is one of the reasons.

In addition, the lesions caused by external influences are often underestimated and not adequately examined. In the course of the disease, the mantle edge syndrome must be differentiated from the spinal paraplegia syndrome. The diagnosis is usually made by an imaging test such as magnetic resonance imaging (MRI). The structure and the functional activity of the cortex are determined and the damage to the outer edge is visible.


Due to the mantle edge syndrome, there are usually various damages and limitations, which mainly occur in the patient’s brain. This damage leads to disturbances of sensitivity and also to paralysis. This paralysis then leads to restricted movement and other limitations in the patient’s everyday life.

Epileptic seizures also occur, which in the worst case can lead to injury or death of the patient. The mantle edge syndrome significantly restricts and reduces the quality of life of those affected. Discomfort can also occur when emptying the bladder or when having a bowel movement, which can also lead to psychological problems. However, mental problems do not occur as a result of the mantle edge syndrome.

Coating edge syndrome is treated by surgical intervention on the patient’s brain. Since this is a very serious procedure, it can also lead to various complications. The tumor cannot be completely removed in every case. In some cases, those affected may then be dependent on diapers. The life expectancy of the patient is not affected by the mantle edge syndrome. The movement restrictions can also be treated with the help of various therapies.

When should you go to the doctor?

Motor disorders are signs of existing irregularities. A doctor’s visit is necessary as soon as there is an impairment of locomotion or signs of paralysis. A doctor is required in the event of pain, impaired perception or discomfort. Further investigations should be carried out to determine the cause. If the foot-lifting muscles can no longer be moved as usual, it is advisable to consult a doctor. In these situations, the affected person experiences a swinging of the leg and has no control over the extremities. To improve your health, you should consult a doctor so that treatment can be initiated immediately.

If, in addition to the leg problems, there are also discrepancies when going to the toilet, these are further symptoms that need to be clarified by a doctor. If the sphincter muscle cannot be subjected to voluntary control or if there are problems with emptying the bladder, a doctor should be consulted. If you become wet or defecate during the day or night, you should consult a doctor. This also applies to children who are still in the growth phase. If you experience seizures, cramps, or feel ill, see a doctor. If there are impairments in the fulfillment of everyday duties or if the well-being decreases significantly, the person concerned should consult a doctor and seek help.

Treatment & Therapy

Treatment of the mantle edge syndrome is carried out individually, depending on the type of damage to the hemisphere. When a brain tumor is diagnosed, the patient undergoes surgery. Here, the meninge genome is surgically completely removed. The edge of the mantle is supplied by the anterior cerebral artery. If this supply is damaged, an attempt is made to restore it.

In the case of bladder and faecal incontinence, medication is administered to try to regulate it. Alternatively, wearing diapers is recommended. The drop foot is accompanied orthopaedically. This reduces the risk of tripping or falling. Orthoses can be an individual support, for example. These are functional electrical stimulators that stimulate the surface of the foot and the muscles. Alternatively, a neuroimplant can be used.

Outlook & Forecast

The prognosis for mania is poor in most patients. Left untreated, it often becomes life threatening. Careless behavior, an increased risk of accidents and a strong overconfidence put those affected in unfavorable situations. Conflicts often arise that lead to legal and health threats for the patient. The actions performed during a manic period result in the sufferer becoming incapacitated. This means that compulsory treatment is necessary in the worst case and can be initiated.

With therapeutic and medical care, the symptoms improve significantly. In addition to the strong euphoric mood, there are often periods of very depressive energy. Many patients are at risk of suicide and are therefore very likely to bring about a premature termination of their lives of their own choosing. Long-term therapy is necessary to establish stability in health. If it is accepted and the patient cooperates in this therapy, the chances of alleviating the health irregularities increase.

Under optimal conditions, there are times when there are no symptoms and a significant improvement in the overall situation. An independent way of life can take place, so that the person concerned is not dependent on any further daily care. Nevertheless, a regression of the existing symptoms can be expected at any time in the course of life.


Basic preventive measures are not to be taken with the coat edge syndrome. If the cause is a brain tumor, there is no prior therapy or indications such as contaminated genetic material that could be taken into account for this rare disease. Since external influences can affect the lesions of the hemispheres, protective measures can be taken here.

Preventive protective measures should be taken especially in activities or places where there are falling objects. In these cases, the skullcap can be protected by wearing a helmet.


As with all tumorous diseases, there is also close follow-up care after treatment in the case of mantle edge syndrome. The aim of this is to build up and permanently guarantee a quality of life despite the illness. In the case of a brain tumor, follow-up checks are therefore carried out several times a year at intervals of a few months.

If no abnormalities are found, the intervals between the next inspection increase. Since the mantle edge syndrome is associated with such severe cuts in everyday life, conditions suitable for everyday use should be developed in the course of aftercare to improve handling of the situation.

Drug treatment will continue to be essential to alleviate any pain that may arise. However, if unusual physical symptoms are noticed outside of the aftercare checks, the doctor treating you should be informed promptly. He will arrange for the follow-up treatment to be intensified as soon as possible.

You can do that yourself

People who suffer from the mantle edge syndrome have only a few options for self-help. If the disease is based on a brain tumor, an operation is necessary. During the treatment period, the doctor’s instructions should be followed to ensure a good recovery.

Since the syndrome is a serious illness, the patient needs not only physical reserves but also sufficient mental strength to deal with the symptoms. A balanced diet rich in vitamins is important to support the immune system. The consumption of pollutants and toxins should be completely avoided.

In particular, the consumption of alcohol or nicotine should be avoided. Emotional stability can be promoted using various relaxation techniques. Qi Gong, autogenic training, yoga or meditation have often proven to be effective. The patient can apply these methods independently and self-determinedly.

Regular exchanges with people they trust or in self-help groups are beneficial for many of those affected. Experiences are discussed and tips for living with the disease are given. Despite the limited options, the patient should pursue leisure activities to improve well-being. Everyday life has to be restructured so that it is geared as optimally as possible to the needs of the patient. Studies have shown that positive thinking and an optimistic attitude are helpful in overcoming the condition.

Mantle Edge Syndrome